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THE EXPERIENCE OF USING SEROLOGICAL MARKERS FOR THE DETECTION OF STOMACHY ATROPHY WITH UNINVASIVE SCREENING IN THE KARACHAY-CHERKESS REPUBLIC

Abstract

The results of screening for non-invasive diagnostics of gastric atrophy with the help of serological biomarkers G-17 - marker of anthral atrophy, gastric atrophy [PG-1], marker of atrophy [PG-2], ratio of PG1 / PG-2 and anti-HPIgG, test system «GastroPanel®».

About the Authors

P. H. Katchieva
SevKavGGTA Medical Institute
Russian Federation


S. M. Kotelevets
SevKavGGTA Medical Institute
Russian Federation


References

1. Сиппонен П. Иммуноферментный анализ на пепсиноген-1, гастрин-17 и антитела к Helicobacterpylori в неинвазивной диагностике атрофического гастрита / П. Сиппонен, Э. Форсблюм, О. Суованейми // Рос. журн. гастроэнтерол., гепатол. и колопроктол. 2002. №3. С.46-51.

2. Syrjanen K. J. A Panel of Serum Biomarkers (GastroPanel®) in Non-invasive Diagnosis of Atrophic Gastritis. Systematic Review and Meta-analysis.Anticancer Res. 2016 Oct;36(10):5133-5144.

3. Syrjanen K. J. Sipponen P, Harkonen M, Peetsalu A, Korpela S. Accuracy of GastroPanel testing in detection of atrophic gastritis. Eur J GastroenterolHepatol 27: 102-104, 2015.

4. Agreus L., Kuipers E.J., Kupcinskas L., Malfertheiner P., DiMario F., Leja M., Mahachai V., Yaron N., van Oijen M., Perez Perez G., Rugge M., Ronkainen J., Salaspuro M., Sipponen P, Sugano K., Sung J.: Rationale in diagnosis and screening of atrophic gastritis with stomach-specific plasma biomarkers. ScandJGastroenterol 47: 136-147, 2012.

5. Леонтьева Н. И., Щербаков И. Т., Новикова Л. И., Грачева Н. М. Хренников Б. Н., Щербакова Э. Г., Потехин П. Л. Оценка инвазивных и неинвазивных методов диагностики хеликобактерной инфекции// Современные технологии медицины. 2011.№2 С.57-60.

6. Vaananen H. Non-endoscopic diagnosis of atrophic gastritis with a blood test. Correlation between gastric histology and serum levels of gastrin-17 and pepsinogen I: a multicentre study / H. Vaananen, M. Vauhkonen, T. Helske // Eur. J. Gastroenterol. Hepatol. 2003. Vol.15. Р 885-891.

7. Why does Japan have a high incidence of gastric cancer? Comparison of gastritis between UK and Japanese patients / G.M. Naylor, T. Gotoda, M. Dixon [et al.] // Gut. 2006. Vol. 55. P. 1545-1552.

8. Ваананен Х. Неэндоскопическая диагностика атрофического гастрита на основании анализа крови: корреляция между результатами гистологического исследования и уровнями гастрина-17 и пепсиногена-1 в сыворотке / Х. Ваананен, М. Ваухко-нен, Т. Хэлске // Клин.перспективы гастроэнтерологии, гепатологии. 2003. Т.4. С.26-32.

9. Correlation of serum pepsinogens and gastrin-17 with atrophic gastritis in gastroesophageal reflux patients: a matched-pairs study / U. Peitz, T. Wex, M. Vieth [et al.] // J GastroenterolHepatol. 2011. Vol. 26. P 82-89.

10. Stepan V. Gastrin biosynthesis in canine G cells / V. Stepan, K. Sugano, T. Yamada // Amer. J. Physiol. Gastrointest. Liver Physiol. 2002. Vol.282. P766-775.

11. Sipponen P Gastric cancer: pathogenesis, risks and prevention / P. Sipponen // J. Gastroenterol. 2002. Vol.37. Suppl.13. P39-44.

12. Eradication of H. pylori infection significantly slows down the progression of precancerous lesions in high risk population: a 5 year prospective randomized study / B.C.Y. Wong, S.K. Lam, W._M. Wong [et al.] // Gastroenterology. 2001. Vol.122. P. A588.

13. Evaluation of optimal gastric mucosal biopsy site and number for identification of Helicobacter pylori, gastric atrophy and intestinal metaplasia / M. Dursun, S. Yilmaz, V. Yukselen [et al.] // Hepatogastroenterology. 2004. Vol.51 (60). P. 1732-1735.

14. Diagnostic accuracy of the serum profile of gastric mucosa in relation to histological and morphometric diagnosis of atrophy / G. Nardone, A. Rocco, S. Staibano [et al.] // Aliment PharmacolTher, 2005. Vol. 22. P. 1139-1146.

15. Gastritis staging in clinical practice: the OLGA staging system / M. Rugge, A. Meggio, G. Pennelli [et al.] // Gut. - 2007. Vol. 56. P 631-636.

16. Noninvasive versus histologic detection of gastric atrophy in a Hispanic population in North America / D.Y. Graham, Z.Z. Nurgalieva, H.M. El-Zimaity [et al.] // ClinGastroenterolHepatol. 2006. Vol. 4. P. 306-314.

17. Usefulness of serum pepsinogens in Helicobacter pylori chronic gastritis: relationship with inflammation, activity, and density of the bacterium / F Di Mario, LG Cavallaro, AM Moussa [et al.] // Dig Dis Sci. 2006. Vol. 51. P. 1791-1795.


Review

For citations:


Katchieva P.H., Kotelevets S.M. THE EXPERIENCE OF USING SEROLOGICAL MARKERS FOR THE DETECTION OF STOMACHY ATROPHY WITH UNINVASIVE SCREENING IN THE KARACHAY-CHERKESS REPUBLIC. Modern Science and Innovations. 2017;(3):156-163. (In Russ.)

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ISSN 2307-910X (Print)