Preview

Modern Science and Innovations

Advanced search

Skin manifestation of gastric cancer (clinical case)

https://doi.org/10.37493/2307-910X.2024.1.10

Abstract

Dermatological reactions are one of the most common manifestations of the paraneoplastic process. Paraneoplastic syndromes include non-oncological diseases that arise under the influence of hormones nd biologically active substances secreted by the tumor. In some cases, paraneoplastic syndrome allows the diagnosis of malignant neoplasm in the early stages, but, unfortunately, it can mask the tumor process with its pronounced manifestations, which leads to the late establishment of the true cause of the disease and belated special treatment. Description of the clinical case. This article will present clinical case of patient with dermatological reactions in gastric cancer. Patient P. 36 years old, complaints of pigmentation of the skin in the neck, armpits, inguinal region and elbow flexions; seizure-like it ching.Three years ago he received treatment for pityriasis versicolor. In this respect, he regarded the changes in the skin as a recurrence of the disease and decided himself used Comfoderm 2, Clotrimazole externally. Diagnosis: Papylar-pigment dystrophy of the skin (black acanthosis). The examination diagnosed Gastric C-r IIIc (T4aN3M0). Conclusion. With the aim of early detection of cancer, it is necessary to improve the qualifications of doctors in general medical care systems in matters of clinical symptoms and diagnostics of paraneoplastic syndrome.

About the Authors

Yu. A. Dykhno
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation

Yuri A. Dykhno – Honored Doctor of the Russian Federation, Dr. Sci. (Medicine), Professor, Professor of the Department of Oncology and Radiation Therapy with a Postgraduate Education Course

Krasnoyarsk

AuthorID: 108203



Yu. Yu. Vinnik
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation

Yuri Yu. Vinnik – Dr. Sci. (Medicine), Professor, Chief Physician, Krasnoyarsk Regional Skin and Venereological Dispensary No. 1; Professor of the Department of Dermatovenerology named after prof. V.I. Prokhorenkov with a Course in Cosmetology and Postgraduate Education Course

Krasnoyarsk

AuthorID: 288354



V. S. Tsykh
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation

Victoria S. Tsikh – Dr. Sci. (Dermat. and Vener.), Postgraduate Student of the Department of Dermatovenerology named after prof. V.I. Prokhorenkov with a Course in Cosmetology and Postgraduate Education Course

Krasnoyarsk

+79131775108



References

1. Barabanau AL, Babko NV, Simchuk II. Some issues of classification, epidemiology, etiopathogenesis and diagnostics of paraneoplastic dermatoses. Dermatovenerology. Cosmetology. 2017;4-s:417-426. (In Russ.).

2. Biryukova NYu, Ivannikova LV, Podkopaeva VV. A case of acanthosis nigricans in a patient with breast carcinoma. Multidisciplinary hospital. 2020;VII(1):59-62. (In Russ.).

3. Bolotnaya LA, Serbina IM. Paraneoplastic dermatosis // International Medical Journal. 2008;3:86-90. (In Russ.).

4. Butov YuS, Azimova TV, Anisimova TV, Chumakov AM. Malignant form of acanthosis nigricans that developed in a patient with bladder cancer. Russian journal of skin and venereal diseases. 2001;2:4-5. (In Russ.).

5. Gaidai AV, Pavlova VYu, Sokolov SV. Paraneoplastic syndrome - prognostic significance. Lechaschi Vrach. 2020;04:66-69. (In Russ.).

6. Derevyankin YuS, Tereshchenko YuA. Paraneoplastic syndromes: a guide for doctors. Krasnoyarsk: Credo; 2003. 46 p. (In Russ.).

7. Malishevskaya NP, Raitseva SS. Paraneoplastic skin changes: prevalence, clinical significance, principles of diagnosis. Modern problems of dermatovenerology, immunology and medical cosmetology. 2009;4(07):46-53.

8. Molochkov VA, Molochkov AV. Clinical dermatoncology. M.: Publisher MDV studio; 2011. 340p. (In Russ.).

9. Mordovtseva VV, Butov YuS. Skin changes in patients with cancer of internal organs. Modern problems of dermatovenerology, immunology and medical cosmetology. 2010;1(08):88-97.

10. Ovsii OG, Guens GP, Korobkova LI, Malyavin AG. Cutaneous Paraneoplastic Lesions (Acanthosis Nigricans Maligna) in Metastatic Cervical Cancer: Clinical Case. Internal Medicine. Clinical Sleep Medicine. 2014;9(97):25- 27.

11. Pritulo OA, Korobkov SA, Marakah Marwan Yakin Nazhi, Sherengovskaya YuV, Tarasova ES. Malignant acanthosis nigricans as the marker of a developing tumor. Klinicheskaya dermatologiya i venerologiya = Russian Journal of Clinical Dermatology and Venereology. 2018;17(5):42-46.

12. Sarian EI. Paraneoplastic dermatosis in the intenist practice // Shìdnoêvropejsʹkij žurnal vnutrìšnʹoï ta sìmejnoï medicini = The East Europe journal of internal and family medicine. 2018;1:86-91.

13. Saribekyan EK, Zubovskaya AG. Acanthosis nigricans in patient with breast cancer and hepatocellular carcinoma. Rossiyskii Zhurnal Kozhnykh i Venericheskikh = Russian Journal of Skin and Venereal Diseases. 2016;19(4):196- 199.

14. Curth HO. Classification of acanthosis nigricans. Int J Dermatol. 1976;15(8):592-593.

15. Maria-Linda Pora, Andrian Claudiu Pora, Cristiana Tanase, Ancuta-Augustina Gheorghisan-Galateanu. Acanthosis nigricans: To be or not to be afraid (Reviev). Oncology Letters. 2019;17:4133-4138.

16. Phiske MM. An approach to acanthosis nigricans. Indian Dermatology Online J. 2014;5(3):239-249.

17. Politzer S. Acanthosis nigricancs, in International Atlas of Rare skin Diseases. London; Lewis and Co; 1891. Part 10: 1–3. (cited: Saribekyan E.K., Zubovskaya A.G., 2016).

18. Association of Oncologists of Russia: clinical recommendations. 2020. Available from: http://oncologyassociation.ru/clinical-guidelines [Accessed 10 January 2024].

19. Oncology Recommendations for supportive and accompanying therapy RUSSCO. Internet portal of the Russian Society of Clinical. Available from: https://rosoncoweb.ru/standarts/suptherapy/ 2021 [Accessed 10 January 2024].


Review

For citations:


Dykhno Yu.A., Vinnik Yu.Yu., Tsykh V.S. Skin manifestation of gastric cancer (clinical case). Modern Science and Innovations. 2024;(1):104-109. (In Russ.) https://doi.org/10.37493/2307-910X.2024.1.10

Views: 151


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2307-910X (Print)