Prognosis of the anti-inflammatory activity of the main components of wormwood by methods of network pharmacology
https://doi.org/10.37493/2307-910X.2023.3.28
Abstract
Of considerable value are "natural bioregulators - traditional herbal medicines with historically proven efficacy and safety." A potential source of biologically active compounds is Artemisiae scopariae herba. Purpose of the study. To predict the probable ways of implementing anti-inflammatory activity for the main active compounds of the extract based on the aerial part of Artemisia scoparia. Free online services, programs and databases: SwissTargetPrediction, GeneCards, DisGeNet, Venny 2.1, STRING, Cytoscape.
Results. The anti-inflammatory effect of the studied compounds, described as the main active substances in the extract from the aerial part of Artemisia scoparia, can probably be realized both through well-known second messengers, primary targets, and through promising targets. Putative targets associated with the manifestation of the anti-inflammatory activity of the extract from Artemisiae scopariae herba have been identified.
About the Authors
E. E. Airapetyan
Volgograd State Medical University of the Ministry of Health of the Russian Federation, Pyatigorsk Medical and Pharmaceutical Institute (branch)
Russian Federation
Russian Federation
Emma E. Airapetyan – Teacher of the Department of Morphology,
Pyatigorsk
D. S. Zolotykh
Volgograd State Medical University of the Ministry of Health of the Russian Federation, Pyatigorsk Medical and Pharmaceutical Institute (branch)
Russian Federation
Russian Federation
Denis S. Zolotykh – PhD in Pharmaceuticals, Associate Professor of the Department of
Toxicological and Analytical Chemistry,
Pyatigorsk
D. A. Konovalov
Volgograd State Medical University of the Ministry of Health of the Russian Federation, Pyatigorsk Medical and Pharmaceutical Institute (branch)
Russian Federation
Russian Federation
Dmitry A. Konovalov – Dr. Sci. (Pharm.), Professor, Head of the Department of Pharmacognosy, Botany and Technology of Herbal Medicines,
Pyatigorsk
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Review
For citations:
Airapetyan E.E., Zolotykh D.S., Konovalov D.A. Prognosis of the anti-inflammatory activity of the main components of wormwood by methods of network pharmacology. Modern Science and Innovations. 2023;(3):283-292. (In Russ.) https://doi.org/10.37493/2307-910X.2023.3.28
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