The prospects of application of spring chistyak Ficaria verna huds in medicine and food industry, chemical composition and biological activity
https://doi.org/10.37493/2307-910X.2022.3.26
Abstract
Ficaria verna is a perennial herbaceous invasive plant widely distributed in Russia. Phenolic (flavonoids, phenolic acids), terpene (triterpene, carotenoids, phytosterols, phthalates) compounds are described as the main groups of biologically active compounds of its aerial part.
The plant was used in folk medicine in some European countries in the treatment of cough, scurvy, hemorrhoids, and also as a hepatoprotective agent. As a toxic substance contained in the plant, protoanemonin is described - an unstable volatile lactone, which is easily converted into a non-toxic compound anemonin.
The study of various extracts from Ficaria verna made it possible to establish their antioxidant, antiinflammatory and antimicrobial activity, which is of undoubted interest for further in-depth study.
The review presents scientific data obtained from available open sources of literature containing information on biologically active substances of a widespread spring chistyak plant. In addition, information is provided on the use of this species and extracts based on it in folk and scientific medicine, established biological and pharmacological activity and toxicity.
About the Authors
D. A. Konovalov
Pyatigorsk Medical and Pharmaceutical Institute - branch of the VolgGMU of the Ministry of Health of Russia
Russian Federation
Russian Federation
Dmitry A. Konovalov - Doctor of Pharmaceutical Sciences, Professor, Deputy Director for Research, Pyatigorsk Medical and Pharmaceutical Institute - branch of the VolgGMU of the Ministry of Health of Russia.
357532, Stavropol Territory, Pyatigorsk, Kalinin Avenue, 11
Tel.: +7 (928) 351-93-49
D. S. Zolotykh
Pyatigorsk Medical and Pharmaceutical Institute - branch of the Volga State Medical University of the Ministry of Health of Russia
Russian Federation
Russian Federation
Denis S. Zolotykh - Candidate of Pharmaceutical Sciences, Associate Professor of the Department of Analytical and Toxicological Chemistry, Pyatigorsk Medical and Pharmaceutical Institute - branch of the Volga State Medical University of the Ministry of Health of Russia.
357532, Stavropol Territory, Pyatigorsk, Kalinin Avenue, 11
Tel.: +7 (928) 351-93-49
D. I. Pozdnyakov
Pyatigorsk Medical and Pharmaceutical Institute - branch of the Volga State Medical University of the Ministry of Health of Russia
Russian Federation
Russian Federation
Dmitry I. Pozdnyakov - Candidate of Pharmaceutical Sciences, Associate Professor of the Department of Pharmacology with a Course in Clinical Pharmacology, Pyatigorsk Medical and Pharmaceutical Institute - branch of the Volga State Medical University of the Ministry of Health of Russia.
357532, Stavropol Territory, Pyatigorsk, Kalinin Avenue, 11
Tel.: +7 (928) 351-93-49
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Review
For citations:
Konovalov D.A., Zolotykh D.S., Pozdnyakov D.I. The prospects of application of spring chistyak Ficaria verna huds in medicine and food industry, chemical composition and biological activity. Modern Science and Innovations. 2022;(3):246-263. (In Russ.) https://doi.org/10.37493/2307-910X.2022.3.26
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