Preview

Modern Science and Innovations

Advanced search

THE STUDY OF INFLUENCE OF PREPARATION «COMBIVIR» ON CARBOHYDRATE AND LIPID METABOLISM OF BLOOD SERUM

Abstract

The purpose of this study was to evaluate the effect of the drug «Combivir» on indicators of carbohydrate metabolism and serum lipids in the systemic toxicity study conducted in conditions of chronic experiment.

About the Authors

Elena Olegovna Sergeeva
GBOU VPO Volgograd state medical University Ministry of health of Russia
Russian Federation


Lubov Anatolievna Sadjaya
GBOU VPO Volgograd state medical University Ministry of health of Russia
Russian Federation


Alexander Yurievich Terekhov
GBOU VPO Volgograd state medical University Ministry of health of Russia
Russian Federation


References

1. Бартлетт Д., Галлант Д., Фамп П. Клинические аспекты ВИЧ-инфекции 2009-2010. - М.: Р. Валент, 2010.

2. Василенко Ю. К. Клинико-биохимические основы патологии и биохимической лабораторной диагностики: учеб. пособие. - Пятигорск: Ротапринт ПятГФА, 2005. - 112 с.

3. Камышников В. С. Справочник по клинико-биохимической лабораторной диагностике: В 2 т. - Минск: Беларусь, 2000. Т. 2. - 463 с.

4. Руководство по проведению доклинических исследований лекарственных средств / под ред. А. Н. Миронова. - М.: Гриф и К, 2012. ч.1. - 944 с.

5. Сернов Л. Н. Элементы экспериментальной фармакологии / Л. Н. Сернов, В. В. Гацура. - М.: Наука, 2000. - 352 с.

6. Chun T. W. et al. Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection. Proceedings of the National Academy of Sciences, 1998, 95(15):8869-8873.

7. Donnell D. et al. Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis. Lancet, 2010, 375(9731):2092-2098.

8. Finzi D. et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nature Medicine, 1999, 5(5):512-517.

9. Hogg R. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet, 2008, 372(9635):293-299.

10. Mocroft A. et al. Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group. Lancet, 1998, 352(9142):1725-1730.

11. Mofenson L. M. et al. Risk factors for perinatal transmission of human immunodefciency virus type 1 in women treated with zidovudine. Pediatric AIDS Clinical Trials Group Study 185 Team. New England Journal of Medicine, 1999, 341(6):385-393.

12. Palella F. J. et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. New England Journal of Medicine, 1998, 338(13):85360.


Review

For citations:


Sergeeva E.O., Sadjaya L.A., Terekhov A.Yu. THE STUDY OF INFLUENCE OF PREPARATION «COMBIVIR» ON CARBOHYDRATE AND LIPID METABOLISM OF BLOOD SERUM. Modern Science and Innovations. 2015;(4):119-125. (In Russ.)

Views: 68


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2307-910X (Print)