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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">msi</journal-id><journal-title-group><journal-title xml:lang="ru">Современная наука и инновации</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Science and Innovations</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2307-910X</issn><publisher><publisher-name>North-Caucasus Federal University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37493/2307-910X.2025.1.11</article-id><article-id custom-type="elpub" pub-id-type="custom">msi-1718</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТЕХНОЛОГИЯ ПРОДОВОЛЬСТВЕННЫХ ПРОДУКТОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>TECHNOLOGY OF FOOD PRODUCTS</subject></subj-group></article-categories><title-group><article-title>Технология инкапсулирования Lactiplantibacillus Plantarum в оболочку альгината кальция для получения микрокапсул различных размеров</article-title><trans-title-group xml:lang="en"><trans-title>The technology of encapsulation of Lactiplantibacillus Plantarum in a calcium alginate shell to produce microcapsules of various sizes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-6005-1814</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорян</surname><given-names>Р. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigorian</surname><given-names>R. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Роза Эмировна Григорян, аспирант, инженер</p><p>кафедра прикладной биотехнологии; факультет пищевой инженерии и биотехнологий имени академика А.Г. Храмцова; научно-исследовательская лаборатория пищевой и промышленной биотехнологии</p><p>Ставрополь</p><p>тел.: +79283058584</p></bio><bio xml:lang="en"><p>Roza E. Grigorian, PHD student, Engineer</p><p>Faculty of Food Engineering and Biotechnology named after Academician A.G.Khramtsov; Research Laboratory of Food and Industrial Biotechnology</p><p>Stavropol</p><p>tel.: +79283058584</p></bio><email xlink:type="simple">roza178225@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4859-2389</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курченко</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurchenko</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Петрович Курченко, кандидат биологических наук, доцент, заведующий НИЛ</p><p>биологический факультет; НИЛ прикладных проблем биологии</p><p>Минск</p><p>тел.: +375296630347</p></bio><bio xml:lang="en"><p>Vladimir P. Kurchenko, Cand. Sci. (Biol.), Associate Professor, Head of the Laboratory</p><p>Department of Biology; Research Laboratory of Applied Problems of Biology </p><p>Minsk</p><p>tel.: +375296630347</p></bio><email xlink:type="simple">Kurchenko@tut.by</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-6564-8544</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головнева</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovnyova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Алексеевна Головнева, кандидат биологических наук, заведующийлабораторией</p><p>лаборатория молочнокислых и бифидобактерий</p><p>Минск</p><p>тел.: +375173991222</p></bio><bio xml:lang="en"><p>Natalya A. Golovnyova, Cand. Sci. (Biol.), Head of the Laboratory</p><p>Laboratory of Lactic Acid Bacteria and Bifidobacteria</p><p>Minsk</p><p>tel.: +375173991222</p><p> </p></bio><email xlink:type="simple">golovnyova@yandex.by</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4385-7250</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисенко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisenko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вера Витальевна Денисенко, научный сотрудник</p><p>лаборатория молочнокислых и бифидобактерий</p><p>Минск</p><p>тел.: +375172431142</p></bio><bio xml:lang="en"><p>Vera V. Denisenko, Researcher</p><p>Laboratory of Lactic Acid Bacteria and Bifidobacteria</p><p>Minsk</p><p>tel.: +375172431142</p></bio><email xlink:type="simple">biochem_lab@mbio.bas-net.by</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9341-9617</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Найденко</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Naidenko</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Инна Александровна Найденко, кандидат биологических наук, ведущий научный сотрудник</p><p>лаборатория молочнокислых и бифидобактерий</p><p>Минск</p><p>тел.: +375172431142</p></bio><bio xml:lang="en"><p>Inna A. Naidenko, Cand. Sci. (Biol.), Leading Researcher</p><p>Laboratory of Lactic Acid Bacteria and Bifidobacteria</p><p>Minsk</p><p>tel.: +375172431142</p></bio><email xlink:type="simple">biochem_lab@mbio.bas-net.by</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-2240-0777</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салманова</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Salmanova</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Динара Александровна Салманова, кандидат технических наук, ассистент, инженер</p><p>кафедра прикладной биотехнологии; факультет пищевой инженерии и биотехнологий имени академика А.Г. Храмцова; научно-исследовательская лаборатория пищевой и промышленной биотехнологии</p><p>Ставрополь</p><p>тел.: +79064624914</p></bio><bio xml:lang="en"><p>Dinara A. Salmanova, Cand. Sci. (Techn.), Assistant, Engineer</p><p>Department of Applied Biotechnology; Faculty of Food Engineering and Biotechnology named after Academician A.G. Khramtsov; Research Laboratory of Food and Industrial Biotechnology</p><p>Stavropol</p><p>tel.: +79064624914</p></bio><email xlink:type="simple">salmanova.dinara@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-5153-0373</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарибян</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Garibian</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лиана Валериковна Гарибян, аспирант, инженер</p><p>кафедра прикладной биотехнологии; факультет пищевой инженерии и биотехнологий имени академика А.Г. Храмцова; научно-исследовательская лаборатория пищевой и промышленной биотехнологии</p><p>Ставрополь</p><p>тел.: +79881172345</p></bio><bio xml:lang="en"><p>Liana V. Garibian, PHD student, Engineer</p><p>Faculty of Food Engineering and Biotechnology named after Academician A.G.Khramtsov; Research Laboratory of Food and Industrial Biotechnology</p><p>Stavropol</p><p>tel.: +79881172345</p></bio><email xlink:type="simple">liana.garibian@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2632-8923</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ржепаковский</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rzhepakovsky</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Игорь Владимирович Ржепаковский, кандидат биологических наук, доцент, ведущий научный сотрудник МНОЛ</p><p>медико-биологический факультет; МНОЛ экспериментальной иммуноморфологии, иммунопатологии и иммунобиотехнологии</p><p>Ставрополь</p><p>тел.: +79054164981</p></bio><bio xml:lang="en"><p>Igor V. Rzhepakovsky, Cand. Sci. (Biol.), Associate Professor, Leading Researcher</p><p>Faculty of Medicine and Biology; Interdepartmental Scientific and Educational Laboratory of Experimental Immunomorphology, Immunopathology and Immunobiotechnology</p><p>Stavropol</p><p>tel.: +79054164981</p></bio><email xlink:type="simple">irzhepakovskii@ncfu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3706-1539</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиева</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Alieva</surname><given-names>L. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Людмила Руслановна Алиева, доктор технических наук, доцент, заместитель декана по международной и инновационной деятельности, ведущий научный сотрудник</p><p>факультет пищевой инженерии и биотехнологий имени академика А.Г. Храмцова; научно-исследовательская лаборатория пищевой и промышленной биотехнологии</p><p>Ставрополь</p><p>тел.: +79624016644</p></bio><bio xml:lang="en"><p>Ludmila R. Alieva, Dr. Sci. (Techn.), Associate Professor, Deputy Dean for International and Innovation Activities, Leading Researcher</p><p>Faculty of Food Engineering and Biotechnology named after Academician A.G.Khramtsov; Research Laboratory of Food and Industrial Biotechnology</p><p>Stavropol</p><p>tel.: +79624016644</p></bio><email xlink:type="simple">ali-ludmila@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8460-2954</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лодыгин</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Lodygin</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Дмитриевич Лодыгин, доктор технических наук, доцент, заведующий кафедрой, главный научный сотрудник</p><p>кафедра прикладной биотехнологии; факультет пищевой инженерии и биотехнологий имени академика А.Г. Храмцова; научно-исследовательская лаборатория пищевой и промышленной биотехнологии</p><p>Ставрополь</p><p>тел.: +79288263918</p></bio><bio xml:lang="en"><p>Aleksey D. Lodygin, Dr. Sci. (Techn.), Associate Professor, Head of the Department, Chief Researcher</p><p>Department of Applied Biotechnology; Faculty of Food Engineering and Biotechnology named after Academician A.G. Khramtsov; Research Laboratory of Food and Industrial Biotechnology</p><p>Stavropol</p><p>tel.: +79288263918</p></bio><email xlink:type="simple">allodygin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3706-1539</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иван Алексеевич Евдокимов, доктор технических наук, профессор, член-корреспондент РАН, заведующий кафедрой, главный научныйсотрудник</p><p>базовая кафедра технологии молока и молочных продуктов; факультет пищевой инженерии и биотехнологий имени академика А.Г. Храмцова; научно-исследовательская лаборатория пищевой и промышленной биотехнологии</p><p>Ставрополь</p><p>тел.: +79624030847</p></bio><bio xml:lang="en"><p>Ivan A. Evdokimov, Dr. Sci. (Techn.), Professor, Head of the Department, Chief Researcher</p><p>Basic Department of Milk and Dairy Products Technology; Faculty of Food Engineering and Biotechnology named after Academician A.G.Khramtsov; Research Laboratory of Food and Industrial Biotechnology</p><p>Stavropol</p><p>tel.: +79624030847</p></bio><email xlink:type="simple">ievdokimov@ncfu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7100-1014</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шрамко</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shramko</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мария Ивановна Шрамко, кандидат биологических наук, доцент, старший научный сотрудник, доцент</p><p>НИЛ пищевой и промышленной биотехнологии; факультет пищевой инженерии и биотехнологий имени академика А.Г. Храмцова; кафедра прикладной биотехнологии</p><p>Ставрополь</p><p>тел.: +79054149526</p></bio><bio xml:lang="en"><p>Maria I. Shramko, Cand. Sci. (Biol.), Associate Professor, Senior Researcher, Associate Professor</p><p>Research Laboratory of Food and Industrial Biotechnology; Faculty of Food Engineering and Biotechnology named after Academician A.G. Khramtsov; Applied Biotechnology Department</p><p>Stavropol</p><p>tel.: +79054149526</p></bio><email xlink:type="simple">marusyashramko@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Кавказский федеральный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Caucasus Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Белорусский государственный университет</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Belarusian State University</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Институт микробиологии НАН Беларуси</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Institute of Microbiology of the National Academy of Sciences of Belarus</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>05</day><month>06</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>135</fpage><lpage>149</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Григорян Р.Э., Курченко В.П., Головнева Н.А., Денисенко В.В., Найденко И.А., Салманова Д.А., Гарибян Л.В., Ржепаковский И.В., Алиева Л.Р., Лодыгин А.Д., Евдокимов И.А., Шрамко М.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Григорян Р.Э., Курченко В.П., Головнева Н.А., Денисенко В.В., Найденко И.А., Салманова Д.А., Гарибян Л.В., Ржепаковский И.В., Алиева Л.Р., Лодыгин А.Д., Евдокимов И.А., Шрамко М.И.</copyright-holder><copyright-holder xml:lang="en">Grigorian R.E., Kurchenko V.P., Golovnyova N.A., Denisenko V.V., Naidenko I.A., Salmanova D.A., Garibian L.V., Rzhepakovsky I.V., Alieva L.R., Lodygin A.D., Evdokimov I.A., Shramko M.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://msi.elpub.ru/jour/article/view/1718">https://msi.elpub.ru/jour/article/view/1718</self-uri><abstract><p>Капсулирование Lactiplantibacillus plantarum в альгинат натрия проводилось методом экструзии с использованием установки ИИ 0.35-1.5 (ООО «МЗТА», г. Муром). Изменяя скорость привода диспергатора, были получены микрокапсулы различных размеров: 805 ± 410, 725 ± 400, 547 ± 300, 304 ± 175 мкм, соответственно. Определена производительность технологии микрокапсулирования, средние размеры полученных гидратированных и сублимированных микрокапсул, их морфологические особенности. Исследовано содержание жизнеспособных клеток в микрокапсулах различного размера.</p></abstract><trans-abstract xml:lang="en"><p> The encapsulation of Lactiplantibacillus plantarum into sodium alginate was carried out by extrusion using the installation AI 0.35-1.5 (LLC "MZTA", Murom). By changing the speed of the dispersant drive microcapsules of various sizes are obtained: 805 ± 410, 725 ± 400, 547 ± 300, 304 ± 175 microns, respectively. The performance of the encapsulation technology, the average sizes of the hydrated and sublimated microcapsules obtained, and their morphological features are determined. The content of viable cells in microcapsules of various sizes has been studied.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инкапсулирование</kwd><kwd>Lactiplantibacillus Plantarum</kwd><kwd>альгинат натрия</kwd><kwd>жизнеспособность лактобактерий</kwd><kwd>пробиотики</kwd><kwd>экструзия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>encapsulation</kwd><kwd>Lactiplantibacillus Plantarum</kwd><kwd>sodium alginate</kwd><kwd>viability of lactobacteria</kwd><kwd>probiotics</kwd><kwd>extrusion</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследования проведены в рамках реализации гранта Министерства науки и высшего образования Российской Федерации «Изучение механизмов взаимодействия молочнокислых микроорганизмов, лактозосбраживающих дрожжей и биологически активных веществ при микроинкапсулировании различных фракций микробиоты», Соглашение № 075-15-2022-1129 от 01. 07. 2022 г.</funding-statement><funding-statement xml:lang="en">The research was carried out within the framework of a grant from the Ministry of Science and Higher Education of the Russian Federation "Studying the mechanisms of interaction of lactic acid microorganisms, lactose-fermenting yeast and biologically active substances during microencapsulation of various fractions of the microbiota", Agreement No. 075-15-2022-1129 dated 01. 07. 2022.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ali U., Saeed M., Ahmad Z., Shah F.-u.-H., Rehman M. 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